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Cornea

Keratoprosthesis (Boston K-PRO)

An artificial cornea that restores vision when a conventional corneal transplant isn't viable or has failed repeatedly. A specialized option for complex corneal cases.

Keratoprosthesis (Boston K-PRO)

What Is a K-PRO Keratoprosthesis?

A K-PRO keratoprosthesis is an artificial cornea implanted to restore vision when a corneal transplant using donor tissue is not a viable option, or when previous transplants have failed repeatedly. The world’s reference model is the Boston Keratoprosthesis (Boston K-PRO), made from clear, biocompatible materials.

It works like an artificial optical window. A transparent device replaces the cloudy or damaged cornea, letting light enter the eye again and reach the retina. It is the last line of defense in corneal surgery, reserved for the most complex cases.

Keratoprosthesis is reserved for situations where a conventional transplant would likely fail:

  • Repeated failure of previous corneal transplants (multiple rejections)
  • Severely damaged ocular surface: chemical burns, Stevens-Johnson syndrome, ocular pemphigoid
  • Extreme dry eye or autoimmune diseases that destroy donor tissue
  • Conditions where donor tissue would not survive

It is an option that restores the hope of vision for patients once considered beyond help.

A Specialized Resource

Keratoprosthesis is not a routine surgery. It requires:

  • Surgeons with specific training in the technique
  • Infrastructure and experience managing complex corneal cases
  • Very close lifelong follow-up

Few centers in the region perform it. Centro Láser offers it as part of its full ladder of corneal solutions, so the most difficult cases are never left without options.

The Procedure

  1. Thorough evaluation: ocular surface condition, intraocular pressure, and retinal and optic nerve function (these must be working for vision to improve).
  2. Surgery: local anesthesia with sedation, or general anesthesia. The prosthesis is assembled with supporting tissue and implanted. The procedure takes 60 to 120 minutes.
  3. Immediate post-op care: rest, a protective contact lens, and antibiotic and anti-inflammatory drops.
  4. Lifelong follow-up: regular checkups to watch for complications (glaucoma, infections, membranes) and keep the implant healthy.

Recovery and Care

Many patients notice improved vision fairly soon, since the prosthesis provides a clear optical window right away. Long-term success, though, depends on rigorous follow-up:

  • Regular lifelong eye exams
  • Permanent use of a protective contact lens, in many cases
  • Prophylactic antibiotic drops
  • Active monitoring for glaucoma and infections

The degree of visual recovery depends on the condition of the retina and optic nerve, which must be functioning.

Why Choose K-PRO Keratoprosthesis at Centro Láser

Centro Láser is one of the few centers in the region that offers K-PRO keratoprosthesis, as part of its cornea department with four fellowship-trained subspecialists. When a conventional corneal transplant is not viable or has failed, keratoprosthesis is the option that keeps the possibility of recovering vision alive. Every case is evaluated individually, with an honest conversation about realistic expectations based on the condition of each eye.

What you should know
about Keratoprosthesis (Boston K-PRO)

It is an artificial cornea, made from clear, biocompatible materials, that is implanted to restore vision when a corneal transplant using donor tissue is not viable. The world's reference model is the Boston K-PRO. It works as an artificial optical "window" that replaces the cloudy or damaged cornea, allowing light to enter the eye again.

When a conventional corneal transplant has a high chance of failing: patients who have already had several rejected transplants, a severely damaged ocular surface (chemical burns, severe autoimmune disease, extreme dry eye), or conditions where donor tissue would not survive. It is an option for cases once considered to have no visual solution.

No. It is a highly specialized procedure that few centers in the region perform. It requires surgeons with specific training and very close, lifelong follow-up. At Centro Láser, we offer it as part of our full ladder of corneal solutions, so our most complex patients are never left without options.

Not during the procedure: it is performed with local anesthesia plus sedation, or general anesthesia. It is major intraocular surgery, so the post-op period requires rest and care. Post-operative pain is managed with the prescribed medication. The most important thing is strict compliance with follow-up visits and eye drops.

Many patients notice improved vision fairly soon, since the prosthesis provides a clear optical window right away. Stabilization and management of the ocular surface, though, take time and require lifelong follow-up. The degree of recovery depends on the condition of the retina and optic nerve, which must be functioning for vision to improve.

Keratoprosthesis requires lifelong follow-up with regular checkups, permanent use of a protective contact lens in many cases, prophylactic antibiotic drops, and monitoring for complications such as glaucoma, infections, or membrane problems behind the prosthesis. The patient's commitment to follow-up care is essential for long-term success.

Because it is a resource for complex cases, it carries greater risks than a standard transplant: glaucoma (the most common, requiring monitoring), intraocular infections, membrane formation behind the prosthesis, and, in some cases, implant retention problems. Close, lifelong follow-up is designed precisely to catch and manage these complications early.

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in Keratoprosthesis (Boston K-PRO)

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